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Future Nat Prod. 2015;1(2): 4-10.
  Abstract View: 148
  PDF Download: 79

Original article

A study of the clinical efficacy of frankincense in the acute phase of ischemic stroke

Nahid Jivad 1, Mahmoud Rafieian-Kopaei 2, Fakhri Rezaei-Kheirabadi 3, Shamsali Khosravi 4, Mahmoud Azizi 5*

1 Neurology Dept., Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, I.R. Iran
2 Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, I.R. Iran
3 General Practitioner, Shahrekord University of Medical Sciences, Shahrekord, I.R. Iran
4 Health Dept., Shahrekord University of Medical Sciences, Shahrekord, I.R. Iran
5 Mycology Dept., Shahid Sadoughi University of Medical Sciences of Yazd, Yazd, I.R. Iran
*Corresponding Author: Mycology Dept., Shahid Sadoughi University of Medical Sciences of Yazd, Yazd, I.R. Iran, Tel.: 00989133533212,, Email: mahmoudaziziy@yahoo.com

Abstract

Background and aims: Ischemic stroke is the most common type of stroke and its most important symptoms are paralysis and movement disorders. Therefore, finding a method for treating this disorder is greatly important. This study was conducted to investigate the clinical efficacy of frankincense on the patients with ischemic stroke.

Methods: In this clinical trial study, 60 patients with ischemic stroke were randomly assigned into two groups of treatment and control (30 patients in each group). In the treatment group, in addition to the routine treatment of stroke, four capsules containing 500 mg of powdered frankincense were used daily, but in the control group, only the treatment of stroke (without frankincense) was implemented. Treatment continued for one month. NIHSS questionnaire (to assess speech and muscle strength) was completed at the baseline, on the seventh day and at the end of treatment for each patient. In this study, statistical analysis was carried out by t- test, chi-square and Mann-Whitney using SPSS software.

Results: The results showed that only in the second step in the treatment group, the rate of recovery of the left lower and muscle strength of upper limbs was significantly increased in patients compared to the control group.

Conclusion: Introducing frankincense into treatment for stroke patients can contribute in improving muscle strength of the patients with muscle weakness in non-dominant hemisphere in acute phase of neurological disorder, while it has no effect improvement of muscle strength of right limbs or speech.


How to cite the article: Jivad N, Rafieian-Kopaei M, Rezaei-Kheirabadi F, Khosravi Sh, Azizi M. Study of the clinical efficacy of frankincense in the acute phase of ischemic stroke. Adv Herb Med. 2015; 1(2): 4-10.
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Submitted: 28 Feb 2015
Accepted: 07 Mar 2015
ePublished: 31 Jul 2015
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