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Future Nat Prod. 2018;4(1): 3-13.
  Abstract View: 183
  PDF Download: 221

Original article

Comparison of antibacterial activity of essential oils of Foeniculum vulgare Mill, Mentha arvensis and Mentha piperita against Streptococcus mutans

Zahra Golestannejad 1, Shahin Gavanji 2, Elmira Mohammadi 3, Amir Motamedi 4, Mehdi Bahrani 4, Fatemeh Rezaei 4, Behrouz Larki 2*, Amin Mojiri 4, Azizollah Bakhtari 5

1 Torabinejad Dental Research Center, Oral and Maxillofacial Medicine Dept., Isfahan University of Medical Sciences, Isfahan, I.R. Iran
2 Young Researchers and Elite Club, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, I.R. Iran
3 Pharmaceutical Biotechnology Dept., Isfahan University of Medical Sciences, Isfahan, I.R. Iran
4 Dentistry Students Research Committee, Isfahan University of Medical Sciences, Isfahan, I.R. Iran
5 Animal Science Dept., Isfahan University of Technology, Isfahan, I.R. Iran
*Corresponding Author: Behrouz Larki. Young Researchers and Elite Club, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, I.R. Iran, Tel: 00989389365450,, Email: larki.behrous@gmail.com

Abstract

Background and aims: Tooth decay is one of the most common chronic diseases around the world and this problem is the result of variety of different bacteria. Streptococcus mutants is one of the most important bacteria which is related to this disease. Finding new effective antibacterial agents is an important area in bioscience for fighting and controlling bacterial infections. Essential oils are most important natural sources of antibacterial agents, particularly against drug-resistant bacteria.

Methods: The aim of this study was to evaluate and compare the antibacterial activity of three essential oils Mentha arvensis, Mentha piperita and Foeniculum vulgare Mill against Streptococcus mutants. Disk diffusion method was carried out and the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were measured.

Results: The results showed that all three essential oils have antibacterial activity against S. mutants. With a constant concentration of 100 µg/µl, the efficiency of Mentha piperita and then Foeniculum vulgare Mill was higher than the efficiency of Mentha arvensis at all 3 given time points (24, 48 and 72 hours). The most effective MIC and MBC were related to Streptococcus mutants using Foeniculum vulgare essential oil which were equal to 8.4 and 14.9 µg/ml, respectively. MIC and MBC for Mentha piperita essential oil were measured 10.5 and 16.3 µg/ml, respectively.

Conclusion: The Essential oils used in present study with different components showed antibacterial activity and therefore they can be used as new antibacterial substances.


How to cite the article: Golestannejad Z, Gavanji S, Mohammadi E, Motamedi A, Bahrani M, Rezaei F, Larki B, Amin Mojiri, Bakhtari A. Comparison of antibacterial activity of essential oils of Foeniculum vulgare Mill, Mentha arvensis and Mentha piperita against Streptococcus mutans. Adv Herb Med. 2017; 3(1): 3-13.
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Submitted: 19 Mar 2017
Accepted: 03 Jun 2017
ePublished: 31 Jan 2018
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