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Future Nat Prod. 2018;4(2): 1-6.
  Abstract View: 525
  PDF Download: 177

Original article

Study the antimicrobial effects of Thyme, Aloe vera and Zararia multiflora extracts against antibiotics resistant Pseudomonas aeruginosa

Ozra Hassanshahian 1*, Fereshteh Javadian 2

1 Horticulture Dept., Shiraz University, Shiraz, I.R. Iran
2 Microbiology Dept., Zabol University of Medical Sciences, Zabol, I.R. Iran
*Corresponding Author: Ozra Hassanshahian. Horticulture Dept., Shiraz University, Shiraz, I.R. Iran, Tel: 00989136245981, , Email: ohasanshahi@gmail.com

Abstract

Background and aims: Resistance of bacteria against antibiotics has always been a prevalent problem in medicine. So, finding new antimicrobial compounds with least side effects seems to be necessary. This paper aims to explore the antimicrobial effects of Thyme, and Aloe vera and Zararia multiflora extracts against Pseudomonas aeruginosa resistant to antibiotics.

Methods: Thyme, and Aloe vera and Z. Multiflora extracts were obtained by using rotary devices. Twenty samples of P. aeruginosa were collected from the patients being cured in Zabol hospitals. The least hindering and killing concentrations of the samples were calculated by lowering their density in sinks. Sensitivity of P. aeruginosa to the different antibiotics prepared by Padtan Teb Co was evaluated by the diffusion disk standard method proposed by Kirby Bauer. Data were analyzed statistically by determination of significant difference using analysis of variance (ANOVA) test. All tests were analyzed at the significance level P<0.05.

Results: Our results have shown that Aloe vera hinders the growth of bacteria in various concentrations. Despite the relative resistance of most of the samples in the used concentrations, the highest sensitivity was observed in 10 and 20 mg/l. Approximately, Aloe vera extract has shown the highest hindrance effect in 5 mg/l. Further, the highest sensitivity to Z. Multiflora was in 10 and 20 mg/l in which 100% of the bacteria were killed. Approximately, Z. Multiflora of 5mg/l had the highest resistive effect.

Conclusion: Thyme, and Aloe vera and Z. Multiflora extracts have considerable antimicrobial effect on the samples of the P. aeruginosa resistant to antibiotics.


How to cite the article: Hassanshahian O, Javadian F. Study the antimicrobial effects of Thyme, Aloe vera and Zararia multiflora extracts against antibiotics resistant Pseudomonas aeruginosa. Adv Herb Med. 2017; 3(2): 1-6.
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Submitted: 15 Jan 2017
Accepted: 01 May 2017
ePublished: 30 Apr 2018
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