Shahrekord University of Medical Sciences Future Natural Products 2783-4662 4 4 2018 10 31 Chemical composition and antibacterial activity of Zygophyllum qatarense Hadidi leaf extract 23 32 EN Rasoul Barzegar Hamid Reza Safaei Maryam Sadat Masoumzadeh Journal Article 2017 09 08 2018 05 22 Background and aims: In present study, chemical composition and antibacterial activity of Zygophyllum Qatarense Hadidi (ZQ) leaf extract were investigated. This study is the first report of evaluation and identification constituent of ZQ leaf that grown in Iran. Methods: Phenolic compounds of methanolic extract of ZQ leaf were identified by High Performance Liquid Chromatography-DAD instrument (HPLC-DAD) and antibacterial activities of this plant against Klebsiella pneumonia and Staphylococcus epidermidis were evaluated by disk diffusion method, MIC and MBC methods. Results: The results showed that this plant contains chlorogenic acid, sinapic acid, caffeic acid, catachin, trans-ferulic acid and rosmarinic acid. The caffeic acid, catachin and rosmarinic acid are significant compound. The results showed methanolic extracts of ZQ leaf have a good potential against K. pneumonia and S. epidermidis. Conclusion: ZQ has a wide range of biological properties and can be used in different industries such as pharmaceutical and food production.