Shahrekord University of Medical Sciences Future Natural Products 2783-4662 2 2 2016 07 31 Determine the effect of aloe Vera and aerobic exercise on lactate de-hydrogenase in male athletes 16 20 EN Amir Hosein Barati Fereshteh Shahidi Mehdi Lotfipour Journal Article 2015 10 02 2015 12 03 Background and aims: Aloe vera is a medicinal plant with antioxidant activity. The aim of this study was to determine the effect of Aloe Vera on lactate de-hydrogenase after a period of aerobic exercise in male athletes. Methods: In this clinical trial study, 20 male students with average weight of 64.85±51 and height of 172.05±6.4 were randomly assigned to 2 groups of Aloe vera supplement (n= 10) and placebo (n= 10). Then aerobic training was conducted for 4 weeks. Then aerobic training was conducted for 4 weeks. In the supplemented group, they were taking 3 capsules, each capsule contains 2 grams of dried Aloe Vera and placebo group were taking 3 capsules containing Dextrin daily after every meal. To determine the index of cell injury marker lactate dehydrogenase (LDH) was determined and blood samples were collected 24 hours before and after each test. The data were analyzed using ANOVA and independent t- test. Significance level was considered as P≤0.05. Results: The findings of this study showed that Aloe Vera caused a significant reduction of lactate de-hydrogenase (p<0.001). The obtained results of research showed that there were no significant differences in the amount of lactate de-hydrogenase (LDH) after doing the exercise protocol. Conclusion: The findings of this study showed that Aloe Vera reduces lactate de-hydrogenase. This result may reflect the role of Aloe Vera as an anti-inflammatory and antioxidant effect.