Shahrekord University of Medical Sciences Future Natural Products 2783-4662 2 2 2016 07 31 Study the anti-microbial effects of Artemisia santonica extract on some pathogenic bacteria 43 46 EN Mehdi Hasanshahian Farshid Khosravi Journal Article 2015 09 15 2015 10 25 Background and aims: It is essential to find new compounds with antimicrobial activity, for rapid growing drug resistance among pathogenic microorganisms. Medicinal herbs application in traditional treatment for thousand years makes this natural compound to the best choice for antimicrobial studies. The aim of this study was to determine the antimicrobial activity of Artemisia against some important pathogenic bacteria. Methods: In the present study, antimicrobial activity of ethanolic and methanolic extracts of A. santonica against 4 pathogenic bacteria was evaluated. A. santonica dry powder was extracted with ethanol and methanol solvents in maceration method. Assessment of antimicrobial efficacies of extracts and MIC were conducted by disk diffusion manual and macro broth dilution method, respectively. Results: Both ethanolic and methanolic extracts could inhibit microorganism in this test. Staphylococcus aureus with MIC=1.56 mg/ml indicates more sensitive to the Artemisia. In addition, Bacillus cereus showed medium sensitivity. E.coli and Pseudomonas Aeruginosa became involved in less sensitivity to the A. santonica extracts. Conclusion: The result of this study confirmed that A. santonica extracts were the best inhibitory effect on S. aureus. Then it can be concluded that by using herbal plant against antibiotics some antibiotic resistant problem can be resolved.